http://support.mobiledefense.com/viewtopic.php?id=569

This tutorial outlines the necessary steps required to install Mobile Defense as a system application. When Mobile Defense is installed as a system application it can auto-enable your location providers (both Wireless and GPS) as needed. This is especially helpful if your device has been lost or stolen, and one or both providers is currently disabled. By following the steps below, you'll also discover that Mobile Defense cannot be uninstalled.